SnapShot: Kinase Inhibitors II

SnapShot: Axon Guidance II

722 Cell 153, April 25, 2013 ©2013 Elsevier Inc. DOI http://dx.doi.org/10.1016/j.cell.2013.04.004 SnapShot: Axon Guidance II Alex L. Kolodkin1 and R. Jeroen Pasterkamp2 1Department of Neuroscience, HHMI, The Johns Hopkins University School of Medicine, Baltimore, MD 21212, USA 2Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrech...

SnapShot: Nuclear Receptors II

Estrogen-related receptors* ERRα/NR3B1; ERRβ/NR3B2; ERRγ/NR3B3 All major systems with specific isoforms showing peaks of expression in metabolic tissues (ERRα and ERRβ) and the CNS (ERRγ) Structurally homologous to estrogen receptors; bind EREs but not activated by estrogens; modulate the expression of enzymes involved in adipogenesis, energy metabolism, and synthesis of lipids, eicosanoids, an...

SnapShot: Microtubule Regulators II

Protein family Biochemical function Representative Proteins H. sapiens D. melanogaster C. elegans A. thaliana S. cerevisiae S. pombe classical microtubule

SnapShot: Cytokines II

SnapShot: Bacterial Appendages II

See online version for legend and references. This two-part SnapShot depicts the assembly and structure of selected nonflagellar surface appendages from gram-negative bacteria. These include chaperone-usher pili and type IV pili (in part I) and the type III secretion needle and type IV secretion pili (in part II). Type III Secretion Needle (Left) Type III pili, also called the needle complex or...